A visionary struggles against the blind in this genre-defining slightly cosy biopic
Director: William Dieterle
Cast: Paul Muni (Louis Pasteur), Josephine Hutchinson (Marie Pasteur), Anita Louise (Annette Pasteur), Donald Woods (Dr. Jean Martel), Fritz Leiber (Dr. Charbonnet), Henry O’Neill (Dr. Emile Roux), Porter Hall (Dr. Rossignol), Raymond Brown (Dr. Radisse), Akim Tamiroff (Dr. Zaranoff), Halliwell Hobbes (Dr. Joseph Lister), Frank Reicher (Dr. Pfeiffer)

Jack Warner was convinced no one would want to watch the life story of some crusty old scientist. But Paul Muni insisted they would – and he was a star – so with a threadbare budget and host of re-used costumes (many not from the correct period) and sets The Story of Louis Pasteur came to the screen – and much to Warner’s surprise was a hit. It can look like an oddly cliché-ridden affair today: until you realise many biopic tropes we’re used to were virtually coined here.
The Story of Louis Pasteur remixes huge portions of Pasteur’s life to make it more dramatic: the man who was the leading scientist in France for almost thirty years is repackaged as an outsider and laughing stock, constantly scorned by the medical establishment until (but of course!) he is triumphantly hailed as a genius by the same doctors who mocked him for years. Sound familiar? The film charts Pasteur’s efforts to discover vaccines, first for anthrax in sheep (leading to a famous test where 25 sheep were vaccinated and 25 were not, then all of them exposed to the disease, killing all the unvaccinated sheep) then rabies in dogs and treating those bitten by rabid dogs. Pasteur uses his unparalleled knowledge of microbes which (but of course!) every other doctor says cannot possibly have anything to do with infection.
There is a lot to enjoy in The Story of Louis Pasteur, an undeniably old-fashioned “Great Men” view of history that manages to turn bacteriology into effective entertainment. It recasts history into an easily digestible tale of visionaries and scoffers – but, crucially, no real baddies – crafting a series of small steps towards scientific discoveries into flashes of inspiration and triumphant revelations. Science is made simple, plain and understandable with Pasteur to talk us through a few shots of microbes under microscopes. At its centre we have a stubborn maverick determined that it is his way or the high-way and who won’t listen for a second to anyone questioning his theories.
There is something rather touching about the film’s admiration for science and celebration of an altruistic quest to make the world a better place. It carefully outlines the dangers of surgery and poor hygiene in medical practice – it opens with a doctor murdered for failing to save his killer’s wife, the reason for his failure pretty clear from the haphazard way he chucks medical equipment into a bag (dropping some of it on the floor en route). This lack of hygiene affects rich and poor (even Duchesses are not safe), in particular women in childbirth. Its truly the enemy of mankind, as a caption explaining the 1870 war stresses (European squabbles being a distant second). This is a problem that is truly noble to take on.
And it motivates Pasteur. Paul Muni is on Oscar-winning form as Pasteur, brilliantly precise and superbly conveying great intelligence mixed with an arrogant self-assurance. But Pasteur’s egotism comes not from vanity but from simply knowing more of which he speaks than anyone else. He’s also a man consumed by a sense of duty to the world: when his work can literally save lives (be they either animal or human) he will not let scorn stand in his way. Muni captures all this wonderfully, creating a prickly man with a playful streak determined to do the right thing the right way (Pasteur may disagree with his critics, but woe-betide their assistants disrespectfully doing the same).
Dieterle’s film crafts a series of excellent set-pieces to present Pasteur as a visionary ahead of his time. To make this really land, he’s therefore completely altered into being seen as a crank and pariah by everyone around him, rather than the influential scientific leader he actually was. This might be poor history, but it’s much better drama. From a furious encounter with Napoleon III (who won’t wear the idea his hand-picked doctors might be wrong about sterilization) to the Medical Academy publicly poo-poohing Pasteur’s outlandish ideas that vaccines might prevent anthrax. To give a face to this mocking of Pasteur (from an establishment we are told is totally wrong on every count) the film invents Dr Charbonnet (well played by Fritz Leiber), an honest but pig-headed critic who exists to be wrong (for noble reasons) on almost every single issue.
Noble as important: this film want to stress everyone acts for decent reasons, so that its final celebration of Pasteur is unblemished by deeply personal rivalry. Charbonnet and Pasteur are both framed as decent men and their relationship allows for plenty of fun melodrama, such as Charbonnet injecting himself with Pasteur’s (fortunately for him) weak rabies sample to ‘expose’ his ideas. When Pasteur’s daughter falls ill in childbirth, but of course Charbonnet is the only doctor available: he humours Pasteur’s sterilisation rules in exchange for a signed letter from Pasteur rubbishing his own theories (Muni’s shuffling flash of conflict that flows across his face at this moment is very well done). But of course, Charbonnet and Pasteur eventually reconcile in honour and decency.
This forms a fun thread throughout the movie, that’s never less than well-staged by Dieterle, with pace and energy. The anthrax test is very dynamic – all celebrating crowds and circus side-shows – and the dramatic appearance of a host of Russian peasants (led by Akim Tamiroff’s bombastic doctor) desperate for a cure for rabies-induced sickness is well-executed. Some beats work less well than others. Donald Woods gets dealt a rotten hand as the dull son-in-law of Pasteur. The women in Pasteur’s family get even worse, with most of Josephine Hutchinson’s lines being of the “stop trying to cure anthrax and come to bed Louis” variety. The costumes are bizarrely all-over-the-place (the women look more like Southern Belles) and there is a reassuring cosiness about everything.
But that’s also one of its most successful features. The Story of Louis Pasteur is a little twee – but it’s also effective. It’s why it laid down a template that worked for countless films that follow (A Beautiful Mind pretty much follows its model and won an Oscar for it 65 years later). That’s because there is also a feel-good factor to see someone who is, without doubt, in the right triumphing over the stubborn. With a great performance by Muni, it’s a rewardingly entertaining biopic.











